Smithtown (31°00′S 152°56′E) is a small town on the banks of the Macleay River in New South Wales, Australia. The town of Gladstone lies across on the southern side of the river. At the 2006 census, Smithtown had a population of 591 people.
The town was named after Robert Burdett Smith, a member of the New South Wales Legislative Assembly, when the post office was established in 1877.
Nestlé has a 90+ year old factory in the town, which is one of the NSW Mid-North Coasts biggest private-sector employers, which traditionally produced Milo. It is now also the only site worldwide that produces Nestlé's "Café Menu" range of products for the whole world.