Mortana is a rural locality in South Australia, located on the Eyre Peninsula. It is traversed by the Flinders Highway. The boundaries for the locality were established in April 2001 in respect of the long established local name.
Mortana Post Office opened on 2 February 1900 and closed on 31 March 1971. A cricket club once existed there, having been founded in 1912; it also formerly had a school. A railway line to the area was mooted in the 1920s, but did not occur.
The Murphy's Haystacks geological formation is located at Mortana, and forms a local tourist attraction.