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Sassafras is a locality and small rural community in the local government area of Latrobe, in the North West region of Tasmania. It is located about 20 kilometres (12 mi) inland from the town of Devonport. The Mersey River forms part of its western boundary, and the Bass Highway passes through from south to north-west. The 2016 census determined a population of 347 for the state suburb of Sassafras.